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sciencedaily.com
Popular anti-aging drug combo caused severe brain damage in mice | ScienceDaily
The findings, published in PNAS, showed that the drug pairing <strong>dasatinib+quercetin (D+Q) damaged myelin</strong>, the protective coating that surrounds nerve fibers and helps electrical signals travel efficiently through the brain and body.
scitechdaily.com
Popular Anti-Aging Treatment May Actually Cause Brain Damage
University of Connecticut scientists report in PNAS that <strong>dasatinib+quercetin (D+Q)</strong> caused significant brain damage in mice, including the loss of myelin, the fatty covering that helps nerve cells send signals quickly and efficiently.
news-medical.net
Anti-aging drug combination causes brain damage in mice
<strong>A two-drug combination frequently used in anti-aging research causes brain damage in mice</strong>, University of Connecticut researchers report in the March 16 issue of PNAS. The findings should make doctors cautious about prescribing the drug combo ...
sciencedaily.com
Scientists boost lifespan by 70% in elderly male mice using simple drug combo | ScienceDaily
In this research, frail mice aged 25 months, which is roughly equivalent to 75 human years, received regular OT+A5i treatment. Male mice treated with this combination lived more than 70% longer than untreated mice and showed marked improvements in agility, endurance, and memory.
frontiersin.org
Frontiers | Rapamycin for longevity: the pros, the cons, and future perspectives
These findings indicate that rapamycin may not be a universal anti-aging solution. Claims of rapamycin as a broadly applicable geroprotector should therefore be tempered by a careful evaluation of risk, mechanism, and both clinical and genetic context. Rapamycin administration initiated in mid-life extends lifespan by 9%–14% in mice and is associated with delayed onset of age-related pathologies (e.g., malignancies and neurodegeneration (Harrison et al., 2009; Wilkinson et al., 2012).
sciencedaily.com
Scientists discover hidden driver of aging — Simple supplement reversed brain decline | ScienceDaily
Research published in PLOS Biology suggests that <strong>declining levels of a brain protein called Menin can trigger inflammation, memory decline, and other age-related changes throughout the body</strong>.
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